Anti-TNF-Alpha Therapy and Systemic Vasculitis

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Anti-TNF-Alpha Therapy and Systemic Vasculitis

TNF-α is a pleiotropic cytokine, which plays a major role in the pathogenesis of numerous autoimmune and/or inflammatory systemic diseases. Systemic vasculitis constitutes a group of rare diseases, characterized by inflammation of the arterial or venous vessel wall, causing stenosis and thrombosis. Treatment of the different type of vasculitis mainly relies on steroids and immunosuppressive dru...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 2014

ISSN: 0962-9351,1466-1861

DOI: 10.1155/2014/493593